The guidelines regarding who should be tested continue to evolve as we learn more about genetics and their role in cancer. If you have a question, ask your primary care physician.
Individuals who might consider genetic testing include:
- All patients diagnosed with breast cancer and/or ovarian cancer.
- An individual with a relative who has a pathogenic variant in a cancer susceptibility gene.
- An individual who has a 1st or 2nd degree relative with any of the following:
- Breast Cancer ≤ 45 y/o
- Ovarian Cancer
- Male Breast Cancer
- Pancreatic Cancer
- ≥2 Breast cancer primaries in a single individual
- ≥2 individuals with breast cancer primaries on the same side of family with at least one diagnose ≤50 y/o
- An individual with a personal and/or family history on the same side of the family of 3 or more of the following (especially if diagnosed age ≤50 y/o; can include multiple primary cancer in same individual)
- Breast cancer, sarcoma, adrenocortical carcinoma, brain tumor, leukemia
- Colon cancer, endometrial cancer, thyroid cancer, kidney cancer, dermatologic manifestations, macrocephaly, or hamartomatous polyps of GI tract.
- Lobular breast cancer, diffuse gastric cancer
- Breast cancer, GI cancer or hamartomatous polyps, ovarian sex chord tumors, pancreatic cancer, testicular sertoli cell tumors or childhood skin pigmentation.